General Information

 


General information

Nordic Immunological Laboratories offer a range of immunologic reagents including:

Contrary to still widely held opinion, immuno­logic reagents are usually not general purpose reagents for universal use. Different tech­niques and even different modifi­cations or arrangements of an otherwise established method frequently result in different require­ments for the reagents. These differences are not only associated with the properties of the antibody, but also with the characte­ristics of other humoral or cellular components under the conditions of the test system.

Inter-species cross-reactivity is a normal feature of antibodies to animal proteins, since homologous proteins of different species frequently share antigenic determinants.
 
plastic tubes containing antisera
 

 


Although cross-reactivity of polyclonal antisera can in principle be removed by cross-adsorption, it is frequently difficult to achieve this even for a single species and it may result in a significant loss of required antibody activity. On the other hand, it can be used to advantage if a comparable primary antiserum is not available and the reaction pattern is correctly recognized and understood.

For use in mixed mouse/human test systems Nordic makes available 7S fractions and immunoconjugates from a goat antiserum to all known mouse Ig-isotypes, cross-adsorbed to minimize reactivity with any component of the human Ig system. The same series of products also exist for the mixed rat/human system.

Antisera, labelled or unlabelled, may be offered in different forms:

 
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